Ethanol → 3-[3,5-dimethyl-4-(4-methyl-piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-(3-chloro-phenyl)-1,3-dihydro-indol-2-one

HRID 112538Notes

Reaction equation

HRID 112538 reaction equation
[CH2:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[CH3:18][c:19]1[c:20]([CH:34]=[O:35])[nH:21][c:22]([CH3:33])[c:23]1[C:24](=[O:25])[N:26]1[CH2:27][CH2:28][N:29]([CH3:32])[CH2:30][CH2:31]1.[CH3:42][CH2:43][OH:44].[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]3[c:13]([cH:14][cH:15][cH:16]2)[NH:12][C:11](=[O:17])[CH2:10]3)[cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]3[c:13]([cH:14][cH:15][cH:16]2)[NH:12][C:11](=[O:17])[C:10]3=[CH:34][c:20]2[c:19]([CH3:18])[c:23]([C:24](=[O:25])[N:26]3[CH2:27][CH2:28][N:29]([CH3:32])[CH2:30][CH2:31]3)[c:22]([CH3:33])[nH:21]2)[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 8082PiperidineHCID 121115823,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehydeHCID 225617984-(3-Chloro-phenyl)-1,3-dihydro-indol-2-one

Product 1

HCID 249426573-[3,5-dimethyl-4-(4-methyl-piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-(3-chloro-phenyl)-1,3-dihydro-indol-2-one

Sources & evidence

ORD record
ord-55c9b2c52bcd41dbbca958d37abe1b0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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