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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1125589Generated: October 30, 2026

Tetrahydrofuran → 2-(4-Fluoro-phenyl)-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid (2-fluoro-5-methoxy-4-methyl-phenyl)-amide

https://huagongshe.com/reaction/1125589

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1-Fluoro-2-isocyanato-4-methoxy-5-methyl-benzeneHCID 59377897—
Reactant2-(4-fluorophenyl)-2,3-dihydro-1H-pyridin-4-oneHCID 66906279—
ReactantButyllithiumHCID 178418339—
Product2-(4-Fluoro-phenyl)-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid (2-fluoro-5-methoxy-4-methyl-phenyl)-amideHCID 66907717—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-1978406f4e5c46f1ba8bf1113e73c1ea
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)