Tetrahydrofuran → (5-Chloro-6-ethenyl-3-pyridinyl)methanol

HRID 1125636Notes

Reaction equation

HRID 1125636 reaction equation
[CH2:20]([N+:21]([CH2:22][CH2:23][CH2:24][CH3:25])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH3:36].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[Cl:1][c:2]1[c:3]([CH:17]=[CH2:18])[n:4][cH:5][c:6]([CH2:8][O:9][Si:10]([C:11]([CH3:12])([CH3:13])[CH3:14])([CH3:15])[CH3:16])[cH:7]1.[F-:19]>>[Cl:1][c:2]1[c:3]([CH:17]=[CH2:18])[n:4][cH:5][c:6]([CH2:8][OH:9])[cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 580017613-Chloro-5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-ethenylpyridine

Product 1

HCID 58001738(5-Chloro-6-ethenyl-3-pyridinyl)methanol

Sources & evidence

ORD record
ord-1b050cfb17924517bc588b46c955fa2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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