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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1125731Generated: November 1, 2026

Hydrochloric Acid → 5-((4-fluorophenyl)(hydroxy)methyl)-N-hydroxy-N,2,2-trimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxamide

https://huagongshe.com/reaction/1125731

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantMethylhydroxylamineHCID 11647—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactantmethyl 5-((4-fluorophenyl) (hydroxy)methyl)-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxylateHCID 67294267—
Product5-((4-fluorophenyl)(hydroxy)methyl)-N-hydroxy-N,2,2-trimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxamideHCID 53327252—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-0ea8591c76224fb89ca49ae8d9ceb03d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)