Hydrochloric Acid → 5-((4-fluorophenyl)(hydroxy)methyl)-N-hydroxy-N,2,2-trimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxamide
Reaction equation
[CH3:12][NH:13][OH:14].[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[ClH:11].[F:15][c:16]1[cH:17][cH:18][c:19]([CH:22]([c:23]2[c:24]3[c:25]([c:26]([C:29]([O:31][CH3:30])=[O:32])[n:27][cH:28]2)[O:33][C:34]([CH3:37])([CH3:38])[O:35][CH2:36]3)[OH:39])[cH:20][cH:21]1.[Li+:10].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH2:40]>>[CH3:12][N:13]([OH:14])[C:29]([c:26]1[c:25]2[c:24]([c:23]([CH:22]([c:19]3[cH:18][cH:17][c:16]([F:15])[cH:21][cH:20]3)[OH:39])[cH:28][n:27]1)[CH2:36][O:35][C:34]([CH3:37])([CH3:38])[O:33]2)=[O:31]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0ea8591c76224fb89ca49ae8d9ceb03d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…