Dichloromethane → (+/-)-3-benzyl-7-chloro-2-{1-[2-(4-fluoro-3-methyl-phenyl)-4,4-dimethyl-4,5 dihydro-imidazol-1-yl]-2-methyl-propyl}-3H-quinazolin-4-one
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:48][CH2:49][Cl:50].[F:37][c:38]1[c:39]([CH3:47])[cH:40][c:41]([C:42]([Cl:43])=[O:44])[cH:45][cH:46]1.[NH2:1][C:2]([CH2:3][NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[c:9]1[n:10][c:11]2[cH:12][c:13]([Cl:27])[cH:14][cH:15][c:16]2[c:17](=[O:26])[n:18]1[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)([CH3:28])[CH3:29]>>[N:1]1=[C:42]([c:41]2[cH:40][c:39]([CH3:47])[c:38]([F:37])[cH:46][cH:45]2)[N:4]([CH:5]([CH:6]([CH3:7])[CH3:8])[c:9]2[n:10][c:11]3[cH:12][c:13]([Cl:27])[cH:14][cH:15][c:16]3[c:17](=[O:26])[n:18]2[CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:3][C:2]1([CH3:28])[CH3:29]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3534ec742cde481187e4bbcdc6eb6cef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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