Potassium Cation → 1-Cyanomethyl-4-diphenylmethoxypiperidine

HRID 112580Notes

Reaction equation

HRID 112580 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[Cl:27][CH2:28][C:29]#[N:30].[K+:25].[K+:26].[c:1]1([CH:7]([O:8][CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([O:8][CH:9]2[CH2:10][CH2:11][N:12]([CH2:28][C:29]#[N:30])[CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 7856ChloroacetonitrileHCID 19660Carbonate IonHCID 30175844-Benzhydryloxypiperidine

Product 1

HCID 111203411-Cyanomethyl-4-diphenylmethoxypiperidine

Sources & evidence

ORD record
ord-ea0ed82e33174e15abe41269d1fe4d3c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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