Ammonium → Dimethyl [2-(2-amino-4-fluorophenyl)-1-phenylethyl]malonate

HRID 1125846Notes

Reaction equation

HRID 1125846 reaction equation
[CH3:30][OH:31].[Cl-:28].[F:1][c:2]1[cH:3][c:4]([N+:25]([O-:26])=[O:27])[c:5]([CH2:8][CH:9]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH:16]([C:17](=[O:18])[O:19][CH3:20])[C:21](=[O:22])[O:23][CH3:24])[cH:6][cH:7]1.[NH4+:29].[Zn:32]>>[F:1][c:2]1[cH:3][c:4]([NH2:25])[c:5]([CH2:8][CH:9]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH:16]([C:17](=[O:18])[O:19][CH3:20])[C:21](=[O:22])[O:23][CH3:24])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 223AmmoniumHCID 312ChlorideHCID 887MethanolHCID 23994ZincHCID 59688514Dimethyl [2-(4-fluoro-2-nitrophenyl)-1-phenylethyl]malonate

Product 1

HCID 58997962Dimethyl [2-(2-amino-4-fluorophenyl)-1-phenylethyl]malonate

Sources & evidence

ORD record
ord-cb45aea9a4a743519a92d425e6466e5b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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