Hydrochloric Acid → 1-(2-Chlorophenyl)-3-(2-piperazin-1-ylethyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide

HRID 1125940Notes

Reaction equation

HRID 1125940 reaction equation
[Cl:1][c:2]1[c:3]([N:8]2[S:9](=[O:32])(=[O:33])[N:10]([CH2:17][CH2:18][N:19]3[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]3)[c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[cH:4][cH:5][cH:6][cH:7]1.[Cl:35][CH2:36][Cl:37].[ClH:34].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[Cl:1][c:2]1[c:3]([N:8]2[S:9](=[O:32])(=[O:33])[N:10]([CH2:17][CH2:18][N:19]3[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]3)[c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 68707981tert-butyl 4-{2-[3-(2-chlorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]ethyl}piperazine-1-carboxylate

Product 1

HCID 578863051-(2-Chlorophenyl)-3-(2-piperazin-1-ylethyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide

Sources & evidence

ORD record
ord-a5aa9b763eb749ceb0ad3c2da09ecc48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…