Methanol → 1-Benzyl-3-bromo-5-(pyrimidin-4-yl)pyridin-2(1H)-one
Reaction equation
[Br:4][c:5]1[c:6](=[O:17])[nH:7][cH:8][c:9](-[c:11]2[n:12][cH:13][n:14][cH:15][cH:16]2)[cH:10]1.[CH3:1][O-:2].[CH3:31][OH:32].[Cl:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Na+:3].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[Br:4][c:5]1[c:6](=[O:17])[n:7]([CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:8][c:9](-[c:11]2[n:12][cH:13][n:14][cH:15][cH:16]2)[cH:10]1Participants
7
Sources & evidence
- ORD record
- ord-b1cd0f048a08458181919f9807e5c3ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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