Acetic Acid → (RS)-Clopidogrel

HRID 1126450Notes

Reaction equation

HRID 1126450 reaction equation
[CH3:24][C:25](=[O:26])[OH:27].[ClH:23].[OH:1][CH:2]1[c:3]2[c:4]([cH:20][cH:21][s:22]2)[CH2:5][N:6]([CH:8]([C:9](=[O:10])[O:11][CH3:12])[c:13]2[c:14]([Cl:19])[cH:15][cH:16][cH:17][cH:18]2)[CH2:7]1>>[CH2:2]1[c:3]2[c:4]([cH:20][cH:21][s:22]2)[CH2:5][N:6]([CH:8]([C:9](=[O:10])[O:11][CH3:12])[c:13]2[c:14]([Cl:19])[cH:15][cH:16][cH:17][cH:18]2)[CH2:7]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 13938216(+/-) Methyl alpha-(7-Hydroxy-4,5,6,7-tetrahydro-5-thieno[3,2-c]pyridyl)-o-chlorophenylacetate

Product 1

HCID 2806(RS)-Clopidogrel

Sources & evidence

ORD record
ord-2b527a879d214c9e9b276260c7391baf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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