Dichloromethane → 4-benzylpiperidine-4-carboxylic acid N',N'-dimethylhydrazide

HRID 1126467Notes

Reaction equation

HRID 1126467 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[NH:16][N:17]([CH3:18])[CH3:19])([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:34]([Cl:35])[Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[NH:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[NH:16][N:17]([CH3:18])[CH3:19])([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 206947194-benzyl-4-(N',N'-dimethylhydrazinocarbonyl)piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 206947064-benzylpiperidine-4-carboxylic acid N',N'-dimethylhydrazide

Sources & evidence

ORD record
ord-9a0ee720ea79495ebf159f80227013c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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