Sodium ion → N-[4-(1-cyano-cyclopropyl)-benzyl]-2,2,2-trifluoro-N-[2-(3-trifluoromethyl-phenyl)-ethyl]-acetamide
Reaction equation
[Br:22][CH2:23][c:24]1[cH:25][cH:26][c:27]([C:30]2([C:33]#[N:34])[CH2:31][CH2:32]2)[cH:28][cH:29]1.[F:3][C:4]([C:5](=[O:6])[NH:7][CH2:8][CH2:9][c:10]1[cH:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][cH:14][cH:15]1)([F:20])[F:21].[H-:1].[Na+:2].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH2:35]>>[F:3][C:4]([C:5](=[O:6])[N:7]([CH2:8][CH2:9][c:10]1[cH:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][cH:14][cH:15]1)[CH2:23][c:24]1[cH:25][cH:26][c:27]([C:30]2([C:33]#[N:34])[CH2:31][CH2:32]2)[cH:28][cH:29]1)([F:20])[F:21]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f3a881ec4990444c8216294ba4c2c90d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…