Water → 1-Boc-4-[6-(trifluoromethyl)-2-pyridyl]piperidin-4-ol
Reaction equation
[Br:1][c:2]1[n:3][c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1.[C:17](=[O:18])([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[N:24]1[CH2:25][CH2:26][C:27](=[O:30])[CH2:28][CH2:29]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH2:31]>>[c:2]1([C:27]2([OH:30])[CH2:26][CH2:25][N:24]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:29][CH2:28]2)[n:3][c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-1393e75247404f73b081e7f8a4fd6e86
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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