Dimethyl Sulfoxide → 1-Ethyl-4-(6-nitropyridin-3-yl)piperazine

HRID 1126933Notes

Reaction equation

HRID 1126933 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1.[CH2:11]([CH3:12])[N:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1.[CH2:30]([N+:31]([CH2:32][CH2:33][CH2:34][CH3:35])([CH2:36][CH2:37][CH2:38][CH3:39])[CH2:40][CH2:41][CH2:42][CH3:43])[CH2:44][CH2:45][CH3:46].[CH3:25][S:26]([CH3:27])=[O:28].[I-:29].[K+:19].[K+:20].[O-:21][C:22]([O-:23])=[O:24].[OH2:47]>>[c:2]1([N:16]2[CH2:15][CH2:14][N:13]([CH2:11][CH3:12])[CH2:18][CH2:17]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 30165Iodide IonHCID 791961-EthylpiperazineHCID 8176205-Bromo-2-nitropyridine

Product 1

HCID 575020861-Ethyl-4-(6-nitropyridin-3-yl)piperazine

Sources & evidence

ORD record
ord-10064211097545468bd4ca9b61b66dec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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