Sodium ion → Tert-butyl 4-[(1-benzylpiperidin-3-yl)methyl]-3-oxopiperazine-1-carboxylate

HRID 1126987Notes

Reaction equation

HRID 1126987 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:14])[NH:11][CH2:12][CH2:13]1.[CH3:17][c:18]1[cH:19][cH:20][c:21]([S:22]([O:23][CH2:28][CH:29]2[CH2:30][N:31]([CH2:35][c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[CH2:32][CH2:33][CH2:34]2)(=[O:24])=[O:25])[cH:26][cH:27]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[H-:15].[Na+:16]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:14])[N:11]([CH2:28][CH:29]2[CH2:30][N:31]([CH2:35][c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[CH2:32][CH2:33][CH2:34]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 3157178Tert-butyl 3-oxopiperazine-1-carboxylateHCID 57656889(1-Benzylpiperidin-3-yl)methyl 4-methylbenzenesulfonate

Product 1

HCID 57656824Tert-butyl 4-[(1-benzylpiperidin-3-yl)methyl]-3-oxopiperazine-1-carboxylate

Sources & evidence

ORD record
ord-e607bb18b37c42ee93940a542d8efc13
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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