HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-[5-(4-n-Butoxybenzenesulfonylamino)-2-ethoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Butoxybenzenesulfonyl Chloride | HCID 517990 | — |
| Reactant | 2-(5-Amino-2-ethoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604941 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[5-(4-n-Butoxybenzenesulfonylamino)-2-ethoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one | HCID 135604938 | — |
Reaction Steps
150 mg (0.424 mmol) of the compound from example 42A are reacted with 186 mg (0.747 mmol) of 4-(n-butoxy)-benzenesulfonyl chloride and 0.34 g (4.30 mmol) of pyridine in 6 ml of tetrahydrofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07098207B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-19738cf49f484ac1b29bcf3080bba171 |
| Source note | uspto-grants-2006_08 |