Toluene → Tert-butyl 4-(6-(1-(4-(trifluoromethyl)phenyl)piperidin-4-yloxy)benzo[d]oxazole-2-carboxamido)piperidine-1-carboxylate
Reaction equation
[CH3:77][c:78]1[cH:79][cH:80][cH:81][cH:82][cH:83]1.[F:41][C:42]([c:43]1[cH:44][cH:45][c:46]([N:49]2[CH2:50][CH2:51][CH:52]([OH:55])[CH2:53][CH2:54]2)[cH:47][cH:48]1)([F:56])[F:57].[O:27]=[C:28]([O:29][CH:30]([CH3:31])[CH3:32])[N:33]=[N:34][C:35]([O:36][CH:37]([CH3:38])[CH3:39])=[O:40].[OH:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([C:9](=[O:10])[NH:11][CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[o:8]2)[cH:25][cH:26]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[O:1]([c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([C:9](=[O:10])[NH:11][CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[o:8]2)[cH:25][cH:26]1)[CH:52]1[CH2:51][CH2:50][N:49]([c:46]2[cH:45][cH:44][c:43]([C:42]([F:41])([F:56])[F:57])[cH:48][cH:47]2)[CH2:54][CH2:53]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-476c37d3a9a2410892409781dc9af418
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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