Hydrochloric Acid → 5-Chloro-2-[4-(3-chloro-pyridin-2-yl)-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole

HRID 1127185Notes

Reaction equation

HRID 1127185 reaction equation
[Cl:17][c:18]1[c:19]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:20][cH:21][cH:22][cH:23]1.[Cl:1][c:2]1[nH:3][c:4]2[c:5]([n:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2.[ClH:16]>>[c:2]1([N:27]2[CH2:26][CH2:25][N:24]([c:19]3[c:18]([Cl:17])[cH:23][cH:22][cH:21][n:20]3)[CH2:29][CH2:28]2)[n:3][c:4]2[c:5]([nH:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 114129441-(3-Chloropyridin-2-yl)piperazineHCID 1785060581H-Benzimidazole, 2,6-dichloro-5-(trifluoromethyl)-

Product 1

HCID 103418275-Chloro-2-[4-(3-chloro-pyridin-2-yl)-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole

Sources & evidence

ORD record
ord-2a2bdbd6fb6340beada6ceea53b3b66b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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