Water → N-[6-(2,3-difluorophenyl)-2-sulfanylidene-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:50][CH2:51][Cl:52].[NH2:8][CH:9]1[C:10](=[S:29])[N:11]([CH2:24][C:25]([F:26])([F:27])[F:28])[CH2:12][CH:13]([c:16]2[c:17]([F:23])[c:18]([F:22])[cH:19][cH:20][cH:21]2)[CH2:14][CH2:15]1.[O:30]=[c:31]1[n:32]([CH:40]2[CH2:41][CH2:42][N:43]([C:46](=[O:47])[Cl:48])[CH2:44][CH2:45]2)[c:33]2[c:34]([n:35][cH:36][cH:37][cH:38]2)[nH:39]1.[OH2:49]>>[NH:8]([CH:9]1[C:10](=[S:29])[N:11]([CH2:24][C:25]([F:26])([F:27])[F:28])[CH2:12][CH:13]([c:16]2[c:17]([F:23])[c:18]([F:22])[cH:19][cH:20][cH:21]2)[CH2:14][CH2:15]1)[C:46]([N:43]1[CH2:42][CH2:41][CH:40]([n:32]2[c:31](=[O:30])[nH:39][c:34]3[c:33]2[cH:38][cH:37][cH:36][n:35]3)[CH2:45][CH2:44]1)=[O:47]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9118c4ffc37241bdacfb85a231ff67e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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