Acetate → 3-Allyl-4-oxo-1-pyridin-2-yl-azetidine-2-carboxylic acid 4-methoxy-benzyl ester

HRID 1127653Notes

Reaction equation

HRID 1127653 reaction equation
[C:40]([O-:41])(=[O:42])[CH3:43].[C:45]([O-:46])(=[O:47])[CH3:48].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][C:9](=[O:10])[CH:11]2[NH:12][C:13](=[O:18])[CH:14]2[CH2:15][CH:16]=[CH2:17])[cH:19][cH:20]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:37][CH2:38][Cl:39].[Cu+2:44].[n:21]1[c:22]([B:27]([OH:28])[OH:29])[cH:23][cH:24][cH:25][cH:26]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][C:9](=[O:10])[CH:11]2[N:12]([c:22]3[n:21][cH:26][cH:25][cH:24][cH:23]3)[C:13](=[O:18])[CH:14]2[CH2:15][CH:16]=[CH2:17])[cH:19][cH:20]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27099Cupric cationHCID 2762745Pyridine-2-boronic acidHCID 178439759HCID 178439759, compound

Product 1

HCID 686039533-Allyl-4-oxo-1-pyridin-2-yl-azetidine-2-carboxylic acid 4-methoxy-benzyl ester

Sources & evidence

ORD record
ord-cbdc5fe08caf4c0fa4737fcba70989ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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