Diethyl Ether → 3-(1-Benzylpiperidin-4-yl)-8-fluoro-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[C:24](=[O:25])([c:26]1[nH:27][cH:28][cH:29][n:30]1)[c:31]1[nH:32][cH:33][cH:34][n:35]1.[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[NH2:1][c:2]1[c:3]([CH2:4][NH:5][CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:10][CH2:11]2)[cH:19][cH:20][cH:21][c:22]1[F:23].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[NH:1]1[c:2]2[c:3]([cH:19][cH:20][cH:21][c:22]2[F:23])[CH2:4][N:5]([CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:10][CH2:11]2)[C:24]1=[O:25]Participants
5
Sources & evidence
- ORD record
- ord-9b412e58b90647d582beb4c465279d43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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