Potassium Cation → 2,6-Dichloro-4-(1-methyl-1H-pyrazol-4-yl)pyridine

HRID 112771Notes

Reaction equation

HRID 112771 reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH2:31]1[O:32][CH2:33][CH2:34][O:35][CH2:36]1.[CH3:10][n:11]1[n:12][cH:13][c:14]([B:16]2[O:17][C:18]([CH3:19])([CH3:20])[C:21]([CH3:22])([CH3:23])[O:24]2)[cH:15]1.[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[Cl:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6]([I:8])[cH:7]1.[K+:29].[K+:30].[OH2:43]>>[Cl:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6](-[c:14]2[cH:13][n:12][n:11]([CH3:10])[cH:15]2)[cH:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27739871-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 117373932,6-Dichloro-4-iodopyridine

Product 1

HCID 866593752,6-Dichloro-4-(1-methyl-1H-pyrazol-4-yl)pyridine

Sources & evidence

ORD record
ord-8c586745be8440b886c4146f229ce3a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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