Ethanol → 4-(2-{[(3,5-Bis-trifluoromethyl-benzyl)-(5-morpholin-4-yl-pyrimidin-2-yl)-amino]-methyl}-4-trifluoromethyl-phenoxy)-butyric acid
Reaction equation
[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[CH3:57][CH2:58][OH:59].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][cH:10][c:11]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[cH:12][n:13]2)[CH2:20][c:21]2[c:22]([O:23][CH2:24][CH2:25][CH2:26][C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:32][cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]2)[cH:40][c:41]([C:43]([F:44])([F:45])[F:46])[cH:42]1)([F:47])[F:48].[Na+:50].[OH-:49]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][cH:10][c:11]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[cH:12][n:13]2)[CH2:20][c:21]2[c:22]([O:23][CH2:24][CH2:25][CH2:26][C:27](=[O:28])[OH:29])[cH:32][cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]2)[cH:40][c:41]([C:43]([F:44])([F:45])[F:46])[cH:42]1)([F:47])[F:48]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-140b559354124c24a7337d8b689400ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…