Dichloromethane → 1-[1-(4-Chloro-phenyl)-cyclopropanecarbonyl]-piperidine-3-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][NH:8][CH2:9][CH2:10][CH2:11]1.[CH:25]([N:26]([CH:27]([CH3:28])[CH3:29])[CH2:30][CH3:31])([CH3:32])[CH3:33].[Cl:12][c:13]1[cH:14][cH:15][c:16]([C:19]2([C:22](=[O:23])[OH:24])[CH2:20][CH2:21]2)[cH:17][cH:18]1.[Cl:34][CH2:35][Cl:36]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][N:8]([C:22]([C:19]2([c:16]3[cH:15][cH:14][c:13]([Cl:12])[cH:18][cH:17]3)[CH2:20][CH2:21]2)=[O:23])[CH2:9][CH2:10][CH2:11]1Participants
5
Sources & evidence
- ORD record
- ord-f1090322cedc4ed38e8d8001a4f03730
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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