Acetonitrile → tert-butyl N-[3-[4-[N-[(6-cyano-2-pyridinyl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]carbamate
Reaction equation
[Br:28][CH2:29][c:30]1[cH:31][cH:32][cH:33][c:34]([C:36]#[N:37])[n:35]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][CH:15]([NH:18][c:19]2[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[CH2:16][CH2:17]1)=[O:27].[CH3:47][C:48]#[N:49].[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][CH:15]([N:18]([c:19]2[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[CH2:29][c:30]2[cH:31][cH:32][cH:33][c:34]([C:36]#[N:37])[n:35]2)[CH2:16][CH2:17]1)=[O:27]Participants
5
Sources & evidence
- ORD record
- ord-2ee88332772042b1a351484ae46a0b72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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