Dichloromethane → Tert-butyl 4-hydroxy-4-{[(3-nitroquinolin-4-yl)amino]methyl}piperidine-1-carboxylate

HRID 1128630Notes

Reaction equation

HRID 1128630 reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[Cl:24][c:25]1[c:26]([N+:35](=[O:36])[O-:37])[cH:27][n:28][c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]12.[Cl:38][CH2:39][Cl:40].[NH2:1][CH2:2][C:3]1([OH:16])[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1>>[NH:1]([CH2:2][C:3]1([OH:16])[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1)[c:25]1[c:26]([N+:35](=[O:36])[O-:37])[cH:27][n:28][c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]12

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 112758084-Chloro-3-nitroquinolineHCID 23396319tert-Butyl 4-(aminomethyl)-4-hydroxypiperidine-1-carboxylate

Product 1

HCID 57515384Tert-butyl 4-hydroxy-4-{[(3-nitroquinolin-4-yl)amino]methyl}piperidine-1-carboxylate

Sources & evidence

ORD record
ord-54f762e6ad8a44b1b707577d2bd127f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…