Dichloromethane → 2-methyl-N-{3-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]oxetan-3-yl}propane-2-sulfonamide
Reaction equation
[CH3:1][C:2]([CH3:3])([CH3:4])[S:5](=[O:6])[NH:7][C:8]1([c:12]2[s:13][c:14](-[c:17]3[cH:18][c:19]([CH3:34])[cH:20][c:21]([NH:23][c:24]4[n:25][cH:26][cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[n:29]4)[cH:22]3)[cH:15][n:16]2)[CH2:9][O:10][CH2:11]1.[Cl:46][CH2:47][Cl:48].[OH:35][O:36][C:37]([c:38]1[cH:39][c:40]([Cl:41])[cH:42][cH:43][cH:44]1)=[O:45]>>[CH3:1][C:2]([CH3:3])([CH3:4])[S:5](=[O:6])([NH:7][C:8]1([c:12]2[s:13][c:14](-[c:17]3[cH:18][c:19]([CH3:34])[cH:20][c:21]([NH:23][c:24]4[n:25][cH:26][cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[n:29]4)[cH:22]3)[cH:15][n:16]2)[CH2:9][O:10][CH2:11]1)=[O:35]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a60aee1b50ab43d58b6159eee11ce5d4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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