Hydrochloric Acid → tert-Butyl 3-(4,4-difluoro-1-piperidyl)azetidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:12])[CH2:11]1.[C:22]([O:23][BH-:24]([O:25][C:26](=[O:27])[CH3:28])[O:29][C:30](=[O:31])[CH3:32])(=[O:33])[CH3:34].[ClH:13].[F:14][C:15]1([F:21])[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[Na+:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:18]2[CH2:17][CH2:16][C:15]([F:14])([F:21])[CH2:20][CH2:19]2)[CH2:11]1Participants
6
Sources & evidence
- ORD record
- ord-815d9802bdb84660b74bcc0ee04ac51f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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