Butyl bromide → 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-butyl-piperidine
Reaction equation
[CH2:18]([CH2:19][CH2:20][CH3:21])[Br:22].[Cl:1][c:2]1[c:3]([C:14]([F:15])([F:16])[F:17])[cH:4][c:5]([CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([C:14]([F:15])([F:16])[F:17])[cH:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([CH2:18][CH2:19][CH2:20][CH3:21])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c1aa45f04309481083d842546c6d712c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…