1-Methylpiperazine → 4-(2-{4-[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-pyrimidin-2-ylamino}-ethyl)-phenol

HRID 1129239Notes

Reaction equation

HRID 1129239 reaction equation
[CH3:25][N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][c:15](-[c:17]3[cH:18][c:19]([CH:20]=[O:21])[cH:22][cH:23][cH:24]3)[n:16]2)[cH:6][cH:7]1>>[OH:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][c:15](-[c:17]3[cH:18][c:19]([CH2:20][N:29]4[CH2:28][CH2:27][N:26]([CH3:25])[CH2:31][CH2:30]4)[cH:22][cH:23][cH:24]3)[n:16]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 866032623-{2-[2-(4-Hydroxy-phenyl)-ethylamino]-pyrimidin-4-yl}-benzaldehyde

Product 1

HCID 586035564-(2-{4-[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-pyrimidin-2-ylamino}-ethyl)-phenol

Sources & evidence

ORD record
ord-337bc4e534a94b22a66874c8e67ebe02
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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