Hydrochloric Acid → Methyl 2-(4-{[(4-bromo-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-6-chloroisonicotinate

HRID 1129352Notes

Reaction equation

HRID 1129352 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]([O:10][c:9]2[c:11]([F:12])[c:13]([F:14])[c:15]([F:16])[c:17]([F:18])[c:19]2[F:20])=[O:21])[nH:5][c:6]1[CH3:7].[ClH:22].[NH2:23][CH:24]1[CH2:25][CH2:26][N:27]([c:30]2[cH:31][c:32]([C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]([Cl:40])[n:39]2)[CH2:28][CH2:29]1>>[Br:1][c:2]1[cH:3][c:4]([C:8](=[O:10])[NH:23][CH:24]2[CH2:25][CH2:26][N:27]([c:30]3[cH:31][c:32]([C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]([Cl:40])[n:39]3)[CH2:28][CH2:29]2)[nH:5][c:6]1[CH3:7]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 86608241Pentafluorophenyl 4-bromo-5-methyl-1H-pyrrole-2-carboxylateHCID 86608261Methyl 2-(4-aminopiperidin-1-yl)-6-chloropyridine-4-carboxylate

Product 1

HCID 86608287Methyl 2-(4-{[(4-bromo-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-6-chloroisonicotinate

Sources & evidence

ORD record
ord-9ee3e553041c46ee91312e20951272aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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