Hydrochloric Acid → cyclohexyl(phenyl)[1-(piperidin-4-ylmethyl)-1H-1,2,4-triazol-3-yl]methanol

HRID 1129377Notes

Reaction equation

HRID 1129377 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][n:15]2[n:16][c:17]([C:20]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)([OH:27])[CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[n:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:35][CH2:36][Cl:37].[ClH:34]>>[NH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][n:15]2[n:16][c:17]([C:20]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)([OH:27])[CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[n:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 59145964Tert-butyl-4-({3-[cyclohexyl(hydroxy)phenylmethyl]-1H-1,2,4-triazol-1-yl}methyl)piperidine-1-carboxylate

Product 1

HCID 59145970cyclohexyl(phenyl)[1-(piperidin-4-ylmethyl)-1H-1,2,4-triazol-3-yl]methanol

Sources & evidence

ORD record
ord-8066098021f842ee9c1c542b0e4fda6e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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