Dimethylformamide → 4-amino-8-((2-(2-chlorophenyl)-8-methyl-quinolin-3-yl)methyl)pyrido[2,3-d]pyrimidin-5(8H)-one
Reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[Cl:19][CH2:20][c:21]1[c:22](-[c:32]2[c:33]([Cl:38])[cH:34][cH:35][cH:36][cH:37]2)[n:23][c:24]2[c:25]([CH3:31])[cH:26][cH:27][cH:28][c:29]2[cH:30]1.[Cs+:17].[Cs+:18].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][cH:10][c:11]2=[O:12].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH2:20][c:21]1[c:22](-[c:32]3[c:33]([Cl:38])[cH:34][cH:35][cH:36][cH:37]3)[n:23][c:24]3[c:25]([CH3:31])[cH:26][cH:27][cH:28][c:29]3[cH:30]1)[cH:9][cH:10][c:11]2=[O:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-680f86a352bd4aaf8d1576cfce972bce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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