Hydrochloric Acid → 4-Hydroxy-2,2-dimethyl-4-[5-[3-methyl-5-[(4-methylpyrimidin-2-yl)amino]phenyl]-1,3-thiazol-2-yl]cyclohexane-1-carboxylic acid

HRID 1129579Notes

Reaction equation

HRID 1129579 reaction equation
[CH3:1][O:2][C:3](=[O:4])[CH:5]1[C:6]([CH3:32])([CH3:33])[CH2:7][C:8]([c:11]2[s:12][c:13](-[c:16]3[cH:17][c:18]([CH3:30])[cH:19][c:20]([NH:22][c:23]4[n:24][cH:25][cH:26][c:27]([CH3:29])[n:28]4)[cH:21]3)[cH:14][n:15]2)([OH:31])[CH2:9][CH2:10]1.[CH3:37][OH:38].[ClH:36].[Na+:35].[OH-:34]>>[O:2]=[C:3]([OH:4])[CH:5]1[C:6]([CH3:32])([CH3:33])[CH2:7][C:8]([c:11]2[s:12][c:13](-[c:16]3[cH:17][c:18]([CH3:30])[cH:19][c:20]([NH:22][c:23]4[n:24][cH:25][cH:26][c:27]([CH3:29])[n:28]4)[cH:21]3)[cH:14][n:15]2)([OH:31])[CH2:9][CH2:10]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 178498222HCID 178498222, compound

Product 1

HCID 674312384-Hydroxy-2,2-dimethyl-4-[5-[3-methyl-5-[(4-methylpyrimidin-2-yl)amino]phenyl]-1,3-thiazol-2-yl]cyclohexane-1-carboxylic acid

Sources & evidence

ORD record
ord-ea63fdf40bbc4ebd9970a80c390b3342
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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