Sodium ion → 2-(4-Fluorophenyl)-3-(2-fluoro-4-pyridinyl)-pyrazolo[1,5-a]pyridine

HRID 1129682Notes

Reaction equation

HRID 1129682 reaction equation
[Br:1][c:2]1[c:3](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[n:4][n:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2.[F:18][c:19]1[n:20][cH:21][cH:22][c:23]([B:25]([OH:26])[OH:27])[cH:24]1.[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[c:2]1(-[c:23]2[cH:22][cH:21][n:20][c:19]([F:18])[cH:24]2)[c:3](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[n:4][n:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 27833962-Fluoropyridine-4-boronic acidHCID 219486782-(4-Fluorophenyl)-3-bromopyrazolo[1,5-a]pyridine

Product 1

HCID 99443962-(4-Fluorophenyl)-3-(2-fluoro-4-pyridinyl)-pyrazolo[1,5-a]pyridine

Sources & evidence

ORD record
ord-5d41c484df0f4644b439320094335212
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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