1-Butanol → N-[1-(6-aminopyrimidin-4-yl)piperidin-3-yl]-2,2,2-trifluoroacetamide
Reaction equation
[CH2:31]([OH:32])[CH2:33][CH2:34][CH3:35].[CH:9]([N:10]([CH:11]([CH3:12])[CH3:13])[CH2:14][CH3:15])([CH3:16])[CH3:17].[Cl:1][c:2]1[cH:3][c:4]([NH2:8])[n:5][cH:6][n:7]1.[F:18][C:19]([C:20](=[O:21])[NH:22][CH:23]1[CH2:24][NH:25][CH2:26][CH2:27][CH2:28]1)([F:29])[F:30]>>[c:2]1([N:25]2[CH2:24][CH:23]([NH:22][C:20]([C:19]([F:18])([F:29])[F:30])=[O:21])[CH2:28][CH2:27][CH2:26]2)[cH:3][c:4]([NH2:8])[n:5][cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-489b1d783c094f9090f74c964cc1b5be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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