Hydrochloric Acid → 1-(4-(Azetidin-3-yloxy)-3-methylbenzyl)pyrrolidine

HRID 1129892Notes

Reaction equation

HRID 1129892 reaction equation
[CH3:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][N:7]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[CH2:8]2)[cH:16][cH:17][c:18]([CH2:20][N:21]2[CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:19]1.[CH3:27][OH:28].[ClH:26]>>[CH3:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][NH:7][CH2:8]2)[cH:16][cH:17][c:18]([CH2:20][N:21]2[CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:19]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 58043113Tert-butyl 3-(2-methyl-4-(pyrrolidin-1-ylmethyl)phenoxy)azetidine-1-carboxylate

Product 1

HCID 666561701-(4-(Azetidin-3-yloxy)-3-methylbenzyl)pyrrolidine

Sources & evidence

ORD record
ord-d409824afe57491dbcd5dc9628e1aba8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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