Dichloromethane → HCID 178499039, compound

HRID 1130158Notes

Reaction equation

[CH3:56][O:57][C:58](=[O:59])[c:60]1[n:61][c:62]2[c:63]([nH:64]1)[cH:65][cH:66][c:67]([NH2:69])[cH:68]2.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:29])[OH:30])[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1.[Cl:70][CH2:71][Cl:72].[c:41]1([P:42]([Cl:43])([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)=[O:50])[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:29])[NH:69][c:67]3[cH:66][cH:65][c:63]4[c:62]([n:61][c:60]([C:58]([O:57][CH3:56])=[O:59])[nH:64]4)[cH:68]3)[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 5

HCID 6344Dichloromethane

HCID 73910Diphenylphosphinic chloride

HCID 81531Diisopropylethylamine

HCID 666882513-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acid

HCID 178499038HCID 178499038, compound

Product 1

HCID 178499039HCID 178499039, compound

Sources & evidence

ORD record: ord-e67627abd2bb433892bc16a36c15b3dc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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