HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10125063, compound → 5-Amino-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(4-methylamino-3,3-dimethyl-1-piperidinyl)-4-oxo-quinoline-3-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10125063 | HCID 10125063 | — |
| Reactant | 5-Amino-1-cyclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxoquinoline-3-carboxylic acid | HCID 10566894 | — |
| Product | 5-Amino-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(4-methylamino-3,3-dimethyl-1-piperidinyl)-4-oxo-quinoline-3-carboxylic Acid | HCID 10137666 | 54% |
Reaction Steps
The condensation of 5-amino-1-cyclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 4-methylamino-3,3-dimethylpiperidine was carried out in a similar manner as described in example 1 (NorA), gave the titled product. Yield 54%, m.p 250° C., C22H29FN4O4, m/z 433 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07098219B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-9e02f934b01a4fad9459c6326aaa2d90 |
| Source note | uspto-grants-2006_08 |