反应详情

1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-{4′-(N-t-butoxycarbonyl-L-alanyl)amino-3′,3′-dimethylpiperidin-1-yl}-4-oxo-quinoline-3-carboxylic acid (0.9 gm) is hydrolysed with 6N HCl (20 ml) at room temperature for 1 hr. The mixture concentrated to furnish the titled product. Yield 75%, m.p 245–50° C., C24H31FN4O5.HCl m/z 475 (M+1).

1. concentrationThe mixture concentrated