Trifluoroacetic acid → 4-Piperazin-1-yl-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1H-benzoimidazole
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([C:39]([F:40])([F:41])[F:42])[cH:17][c:18]3[nH:19][c:20]([N:23]4[CH2:24][CH2:25][N:26]([c:29]5[n:30][cH:31][cH:32][cH:33][c:34]5[C:35]([F:36])([F:37])[F:38])[CH2:27][CH2:28]4)[n:21][c:22]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[OH:43][C:44]([C:45]([F:46])([F:47])[F:48])=[O:49]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([C:39]([F:40])([F:41])[F:42])[cH:17][c:18]3[nH:19][c:20]([N:23]4[CH2:24][CH2:25][N:26]([c:29]5[n:30][cH:31][cH:32][cH:33][c:34]5[C:35]([F:36])([F:37])[F:38])[CH2:27][CH2:28]4)[n:21][c:22]23)[CH2:12][CH2:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b1e945d8199c48e284c560911acfa7f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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