Water → 4-Benzyloxycarbonyl-1-(4-fluorobenzyl)-3,4-dihydropyrazin-2(1H)-one

HRID 1130497Notes

Reaction equation

HRID 1130497 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH2:12][C:13](=[O:14])[N:15]([CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[CH2:24][CH:25]([O:26][CH3:27])[O:28][CH3:29].[CH3:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1.[OH2:30].[c:31]1([CH3:32])[cH:33][cH:34][c:35]([S:36]([OH:37])(=[O:38])=[O:39])[cH:40][cH:41]1.[c:42]1([CH3:43])[c:44]([S:45]([OH:46])(=[O:47])=[O:48])[cH:49][cH:50][cH:51][cH:52]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][C:13](=[O:14])[N:15]([CH2:16][c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[CH:24]=[CH:25]1

Participants

6

Reactant 5

HCID 962WaterHCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 69252-Methylbenzenesulfonic acidHCID 59813049N2-Benzyloxycarbonyl-N1-(2,2-dimethoxyethyl)-N1-(4-fluorobenzyl)-glycinamide

Product 1

HCID 598130504-Benzyloxycarbonyl-1-(4-fluorobenzyl)-3,4-dihydropyrazin-2(1H)-one

Sources & evidence

ORD record
ord-7dc37f25c23e4fa1bd3aae3633d56777
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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