Bromide ion → 4-[(3-Fluorophenyl)methyl]-5-(4-methylsulfonylphenyl)-2-(2,2,2-trifluoroethyl)pyridazin-3-one
Reaction equation
[Br-:24].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH2:39]([Cl:40])[Cl:41].[F:1][C:2]([CH2:3][n:4]1[n:5][cH:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([S:18](=[O:19])(=[O:20])[CH3:21])[cH:16][cH:17]2)[c:8]([Cl:11])[c:9]1=[O:10])([F:22])[F:23].[F:25][c:26]1[cH:27][c:28]([CH2:29][Mg+:30])[cH:31][cH:32][cH:33]1>>[F:1][C:2]([CH2:3][n:4]1[n:5][cH:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([S:18](=[O:19])(=[O:20])[CH3:21])[cH:16][cH:17]2)[c:8]([CH2:29][c:28]2[cH:27][c:26]([F:25])[cH:33][cH:32][cH:31]2)[c:9]1=[O:10])([F:22])[F:23]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7f8a8f96d5c341088a3ae98baf1a1df3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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