1,2-Dimethoxyethane → HCID 57807917, compound

HRID 1130787Notes

Reaction equation

HRID 1130787 reaction equation
[CH3:113][O:114][CH2:115][CH2:116][O:117][CH3:118].[F:19][C:20]([c:21]1[cH:22][c:23]([B:31]([OH:32])[OH:33])[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1)([F:34])[F:35].[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([NH:11][c:12]1[n:13][cH:14][cH:15][c:16]([I:18])[cH:17]1)[cH:10]2.[Pd:36].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1.[c:75]1([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[cH:89][cH:90][cH:91][cH:92][cH:93]1.[c:94]1([P:95]([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[cH:108][cH:109][cH:110][cH:111][cH:112]1>>[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([NH:11][c:12]1[n:13][cH:14][cH:15][c:16](-[c:23]3[cH:22][c:21]([C:20]([F:19])([F:34])[F:35])[cH:26][c:25]([C:27]([F:28])([F:29])[F:30])[cH:24]3)[cH:17]1)[cH:10]2

Participants

6

Reactant 5

HCID 80711,2-DimethoxyethaneHCID 11776Triphenylphosphine4×HCID 23938PalladiumHCID 1562653,5-Bis-trifluoromethylphenylboronic acidHCID 57808271(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-(4-iodo-pyridin-2-yl)-amine

Product 1

HCID 57807917HCID 57807917, compound

Sources & evidence

ORD record
ord-da84f5422dd64c9eb983c6a277918389
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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