Dimethylformamide → 4-Bromo-1-chloro-2-[[4-(2,2,2-trifluoroethoxy)phenyl]methyl]benzene

HRID 113098Notes

Reaction equation

HRID 113098 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:16])[c:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)[cH:7]1.[C:17](=[O:18])([O-:19])[O-:20].[CH3:23][c:24]1[cH:25][cH:26][c:27]([S:28]([O:29][CH2:34][C:35]([F:36])([F:37])[F:38])(=[O:30])=[O:31])[cH:32][cH:33]1.[Cs+:21].[Cs+:22].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:16])[c:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:34][C:35]([F:36])([F:37])[F:38])[cH:13][cH:14]2)[cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 67942Ethanol, 2,2,2-trifluoro-, 1-(4-methylbenzenesulfonate)HCID 104967Cesium cation2×HCID 574237514-((5-Bromo-2-chlorophenyl)methyl)phenol

Product 1

HCID 866851464-Bromo-1-chloro-2-[[4-(2,2,2-trifluoroethoxy)phenyl]methyl]benzene

Sources & evidence

ORD record
ord-75e1ee95cb6740278452bea37cdcbd44
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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