Tributylphosphine → {6-[4-bromo-2-methyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester
Reaction equation
[Br:17][c:18]1[c:19]([CH2:34][OH:35])[n:20]([CH3:33])[n:21][c:22]1-[c:23]1[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]1.[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][c:14]12)=[O:16].[CH2:36]([P:37]([CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH2:44][CH3:45])[CH2:46][CH2:47][CH3:48]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:34][c:19]3[c:18]([Br:17])[c:22](-[c:23]4[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]4)[n:21][n:20]3[CH3:33])[cH:13][c:14]12)=[O:16]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-c35042e1cf3042b080471d8ade819f4e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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