Hydrochloric Acid → 2-[(1-Methyl-1H-indazol-5-yl)oxy]-3-pyridinemethanamine

HRID 1131564Notes

Reaction equation

HRID 1131564 reaction equation
[CH3:1][n:2]1[n:3][cH:4][c:5]2[cH:6][c:7]([O:11][c:12]3[c:13]([C:14]#[N:15])[cH:16][cH:17][cH:18][n:19]3)[cH:8][cH:9][c:10]12.[CH3:21][OH:22].[ClH:20].[OH-:23].[OH-:24].[Pd+2:25]>>[CH3:1][n:2]1[n:3][cH:4][c:5]2[cH:6][c:7]([O:11][c:12]3[c:13]([CH2:14][NH2:15])[cH:16][cH:17][cH:18][n:19]3)[cH:8][cH:9][c:10]12

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 574187422-(1-Methyl-1H-indazol-5-yloxy)-nicotinonitrile

Product 1

HCID 674103932-[(1-Methyl-1H-indazol-5-yl)oxy]-3-pyridinemethanamine

Sources & evidence

ORD record
ord-9ec21c233ba84cecb185f50c000fce75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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