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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1132279Generated: October 31, 2026

Methyl iodide → trans-2-{4-[Methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-cyclohexyloxy}-propionic acid tert-butyl ester

https://huagongshe.com/reaction/1132279

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactanttrans-{4-[Methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-cyclohexyloxy}-acetic acid tert-butyl esterHCID 69285957—
Producttrans-2-{4-[Methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-cyclohexyloxy}-propionic acid tert-butyl esterHCID 69283815—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-893cd88dc95d43d0b6bc3f542e441165
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)