Methyl iodide → trans-2-{4-[Methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-cyclohexyloxy}-propionic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][O:8][CH:9]1[CH2:10][CH2:11][CH:12]([N:15]([S:16](=[O:17])(=[O:18])[c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[CH3:29])[CH2:13][CH2:14]1)=[O:30].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[I:41][CH3:42].[Li+:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([O:8][CH:9]1[CH2:10][CH2:11][CH:12]([N:15]([S:16](=[O:17])(=[O:18])[c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[CH3:29])[CH2:13][CH2:14]1)[CH3:31])=[O:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-893cd88dc95d43d0b6bc3f542e441165
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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